Magnetic nanoparticles for drug delivery applications

Namdeo, Mini (Polymer Research Lab., Department of Chemistry, Government Model Science College); Saxena, Sutanjay; Tankhiwale, Rasika; Bajpai, M.; Mohan, Y.M.; Bajpai, S.K.

Source: Journal of Nanoscience and Nanotechnology, v 8, n 7, July, 2008, p 3247-3271

ISSN: 1533-4880

Publisher: American Scientific Publishers

Abstract: In recent past magnetic nanoparticles have been explored for a number of biomedical applications due to their superparamagnetic moment with high magnetic saturation value. For these biomedical applications, magnetic nanoparticles require being monodispersed so that the individual nanoparticle has almost identical physico-chemical properties for biodistribution, bioelimination and contrast imaging potential. Further, the surface functionalization/modification of magnetic nanoparticles ultimately facilitate the protein or DNA separation, detection and magnetic resonance imaging contrast, drug delivery and hyperthermia applications. The essential goal of this review is to evaluate the recent advances of magnetic nanoparticles for tumor, brain targeting and hyperthermia applications. Copyright © 2008 American Scientific Publishers All rights reserved. (233 refs.)

terms:  Nanoparticles  -  Applications  -  Atoms  -  Chemical properties  -  Drug delivery  -  Drug therapy  -  Hyperthermia therapy  -  Magnetic materials  -  Magnetic resonance imaging  -  Magnetic resonance  -  Magnetism  -  Nanostructured materials  -  Nanostructures  -  Nucleic acids  -  Organic acids  -  Resonance  -  Saturation magnetization  -  Superparamagnetism  -  Tumors